|
KMID : 0363219750130030211
|
|
Korean Journal of Dermatology
1975 Volume.13 No. 3 p.211 ~ p.215
|
|
|
Two Cases of Juvenile Xanthogranuloma
|
|
金蘭姬/Kim, Nan Hee
金秀男/兪泰演/梁文浩/Kim, Soo Nam/Yoo, Tae Yun/Yang, Moon Ho
|
|
|
Abstract
|
|
|
Two Cases of Juvenile Xanthogranuloma(JXG). are reported with review of literatures. JXG is a rare disease, and have not yet been reported in this country.
Case Ⅰ : Two months old healthy female infant has two firm, discrete, brownish yellow waxy nodules on the left postauricular region and the left forearm. The lesion had begun as erythematous pinhead sized papules, and have been enlarged rapidly to pea siez during last three weeks.
Case Ⅱ : Three year old healthy male has firm, discrete, pinhead to pea sized scattered 16 papules and nodules on the trunk and right side of neck.
Laboratory findings and X-ray studies were normal in both cases and there were no evidence of metabolic disorder or bony abnormality.
Histopathologic studies show similar findings in both cases.
In hematoxylin-eosin staining, epidermis shows parekeratosis and slight elongation of rete ridges with suprapapillary thinning with focal spongiosis and invasion of -inflammatory cells. The entire dermis, from dermal papillae to subcutis, is replaced -by granulomatous lesion composed with histiocytes and a few giant cell reaction, in ad-,dition to histiocytic proliferation, considerable amount of eosinophils are infiltrated with some lymphocytes and plasma cells. The dermal collagen fibers are partly degenerated. In -the upper most portion, some foamy histiocytes are also seen.
In frozen section and Sudan M fat staining, the tissue shows mild reactivities.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|